Nestled in the vibrant heart of Tribeca, this stunning loft residence at 110 Duane Street #2 seamlessly blends modern luxury with historic charm, offering an unparalleled living experience in one of New York Citys most coveted neighborhoods. Entering through your private key elevator, you arrive at a spacious 5-bedroom, 3-bathroom home, ensuring both privacy and tranquility. The primary bedroom features a generously sized walk-in closet, complete with a hidden door that leads to a luxurious en-suite bathroom. The bathroom is designed with sophistication, offering a standing shower, separate tub, and double vanity sinks, creating a spa-like retreat. The expansive open-concept layout connects the living, dining, and kitchen areas, promoting functionality and efficiency, with smart home technology integrated throughout. The Boffi-designed kitchen is a chefs dream, equipped with premium Miele appliances, Dornbracht fixtures, a grey travertine backsplash, and sleek white quartz countertopsideal for hosting and entertaining. A generous pantry and a large laundry room add convenience and comfort to this well-designed home. Located just steps from Duane Park, this residence provides easy access to transportation, acclaimed restaurants, trendy cafes, upscale boutiques, and vibrant nightlife. Hudson River Park is a short stroll away, offering scenic walking paths, while the neighborhood's renowned art galleries contribute to the area's dynamic cultural scene. This Tribeca loft combines luxurious living with an unbeatable locationan extraordinary opportunity to enjoy the best of New York City living.